Pencegahan Abortus pada Awal Kehamilan

Nuswil Bernolian, Wim T. Pangemanan, Ahmad Kurdi Syamsuri, M. Hatta Ansyori, Putri Mirani, Peby Maulina Lestari, Abarham Martadiansyah, Cindy Kesty


Abstract


Abortus merupakan suatu kejadian terminasi kehamilan dengan usia kehamilan <20 minggu dan berat janin <500 g. Angka kejadian abortus disebutkan sekitar 15% dari seluruh kehamilan. Terdapat beberapa faktor risiko abortus yaitu faktor risiko yang dapat dimodifikasi dan tidak dapat dimodifikasi. Beberapa faktor risiko yang dapat dimodifikasi yaitu faktor nutrisi, konsumsi kafein, alkohol, kebiasaan merokok, infeksi, paparan radiasi, beban kerja, dan pengaruh obat-obatan. Beberapa faktor risiko yang tidak dapat dimodifikasi, yaitu genetik, kelainan kongenital, dan lain-lain. Dengan mengetahui faktor risiko tersebut, dokter dapat melakukan pencegahan dan intervensi yang sesuai dengan kondisi masing-masing pasien yang mengalami abortus. Metode yang digunakan adalah tinjauan pustaka dengan menggunakan beberapa database seperti Pubmed, Wiley Online Library, dan ScienceDirect dari 10 tahun terakhir.

Prevention of Miscarriage in Early Pregnancy

Abstract
Miscarriage is an event of termination of pregnancy with < 20 weeks of gestation and fetal weight < 500 grams. The incidence of miscarriage is around 15% of all pregnancies. There are several risk factors for miscarriage, namely modifiable and non-modifiable risk factors. Some modifiable risk factors are nutritional factors, consumption of caffeine, alcohol, smoking habit, infection, radiation exposure, workload, and the influence of drugs. Several risk factors that can not be modified, namely genetics, congenital abnormalities, and others. By knowing these risk factors, doctors can carry out prevention and intervention according to the conditions of each patient who undergoes miscarriage. The method used is a literature review using several databases such as Pubmed, Wiley Online Library, and ScienceDirect from the last 10 years.

Key words: miscarriage, prevention, risk factors, pregnancy.

Keywords


abortus, pencegahan, faktor risiko, kehamilan.

Full Text:

PDF

References


Cunningham F. Gary, Kenneth JL, Steven LB, Jodi SD, Barbara LH, Brian MC, et al. Williams obstetrics. 25th edition. New York: McGraw-Hill Education, 2018.

Garcı́a-Enguı́danos A, Calle M, Valero J, Luna S, Domı́nguez-Rojas V. Risk factors in miscarriage: a review. Eur J Obstet Gynecol Reprod Biol.. 2002;102(2):111-9.

World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience. Geneva; 2016.

Maconochie N, Doyle P, Prior S, Simmons R. Risk factors for first trimester miscarriage-results from a UK-population-based case-control study. BJOG. 2007;114(2):170-186.

Lashen H. Obesity is associated with increased risk of first trimester and recurrent miscarriage: Matched case-control study. Human Reprod. 2004;19(7):1644-6.

Rasch V. Cigarette, alcohol, and caffeine consumption: Risk factors for spontaneous abortion. Acta Obstet Gynecol Scand. 2003;82(2):182-8.

Abel EL. Maternal alcohol consumption and spontaneous abortion. Alcohol. 1997;32:211–9.

Pineles B, Park E, Samet J. Systematic review and meta-analysis of miscarriage and maternal exposure to tobacco smoke during pregnancy. Am J Epidemiol. 2014;179(7):807-823.

Wang L, Yang Y, Liu F, Yang A, Xu Q, Wang Q, et al. Paternal smoking and spontaneous abortion: A population-based retrospective cohort study among non-smoking women aged 20–49 years in rural China. J Epidemiol Community Health. 2018;72(9):783-9.

Carp H. Progestogens in the prevention of miscarriage. Horm Mol Biol Clin Investig. 2016;27(2).

Masfiah S, Anandari D, Aji T. Does prenatal care package in indonesia reduce miscarriage/stillbirth?. Management in Health. 2015;XIX/1 pp: 34-37

Li D, Chen H, Ferber J, Odouli R, Quesenberry C. exposure to magnetic field non-ionizing radiation and the risk of miscarriage: A prospective cohort study. Sci Rep. 2017;7(1).

Giakoumelou S, Wheelhouse N, Cuschieri K, Entrican G, Howie S, Horne A. The role of infection in miscarriage. Hum Reprod Update. 2015;22(1):116-33.

Qu F, Wu Y, Zhu Y, Barry J, Ding T, Baio G, et al. The association between psychological stress and miscarriage: A systematic review and meta-analysis. Sci Rep. 2017;7(1).

Bonde JP, Jørgensen KT, Bonzini M, Palmer KT. Miscarriage and occupational activity: A systematic review and meta-analysis regarding shift work, working hours, lifting, standing, and physical workload. Scand J Work Environ Health. 2012;39(4):325-34.

Li D, Ferber J, Odouli R, Quesenberry C. Use of nonsteroidal antiinflammatory drugs during pregnancy and the risk of miscarriage. Am J Obs Gynecol. 2018;219(3):275.e1-275.e8.

Hyde KJ, Schust DJ. Genetic considerations in recurrent pregnancy loss. Cold Spring Harb Perspect Med. 2015;5(3):a023119.

Grimstad F, Krieg S. Immunogenetic contributions to recurrent pregnancy loss. J Assist Reprod Genet. 2016;33(7):833-47.

Bashiri A, Halper KI, Orvieto R. Recurrent implantation failure-update overview on etiology, diagnosis, treatment and future directions. Reprod Biol Endocrinol. 2018;16(1):121.




DOI: http://dx.doi.org/10.24198/obgynia/v6.n3.403

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.


     
     

Creative Commons License
Indonesian Journal of Obstetrics & Gynecology Science is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
  Web Analytics
  View My Stat