Optimal Maternal-Fetal Interface Environment Affects Neonatal Viability in Preterm Preeclampsia and IUGR Pregnancy

Novi Resistantie,(1*) Semuel Semuel,(2) Cindy Fawwaz Roviqoh,(3) Taufik Ramdani,(4)

(1) Bhayangkara Tk.I R. Said Sukanto Police Hospital Jakarta
(2) Bhayangkara Tk.I R. Said Sukanto Police Hospital Jakarta
(3) Bhayangkara Tk.I R. Said Sukanto Police Hospital Jakarta
(4) Faculty of Medicine Universitas Pembangunan Nasional Veteran Jakarta
(*) Corresponding Author

Abstract


Objective: to report rare case of fetal viability on preterm pregnancy with preeclampsia and IUGR
Methods: case report
Case: A 29-year-old woman (G1P0A0) at 29 weeks of gestation, came to the Obstetrics and Gynecology Outpatient Clinic of Bhayangkara Tk. I R. Said Sukanto Police Hospital Jakarta with complaints of left-sided headache since 25 weeks of gestation. After examination, the patient was diagnosed with preeclampsia with IUGR. The caesaria section was performed at 28 weeks and a baby was born with BW: 850 grams, BL: 31 cm, and an APGAR score of 5/6. No inflammatory cells were found in chorionic villi. The baby continues to live after being treated in the NICU for 30 days.
Conclusion: Optimal maternal fetal interface environment secures neonatal viability.

Lingkungan Antarmuka Maternal-Fetal yang Optimal Mempengaruhi Kelangsungan Hidup Neonatal pada Kehamilan Prematur dengan Preeklamsia dan IUGR

Abstrak
Tujuan: untuk melaporkan kasus jarang viabilitas fetus pada kehamilan preterm dengan preeklampsia dan IUGR
Metode: laporan kasus
Kasus: Seorang perempuan berusia 29 tahun (G1P0A0) dengan usia kehamilan 29 minggu, datang ke Poliklinik Obstetri dan Ginekologi Rumah Sakit Bhayangkara Tk. I R. Said Sukanto Jakarta mengalami pusing pada kepala sebelah kiri sejak usia kehamilan 25 minggu. Setelah pemeriksaan, pasien didiagnosa mengalami preeklamsia dengan perburukan IUGR. Operasi Seksio sesarea dilakukan pada usia kehamilan 28 minggu dan lahir seorang bayi dengan BB: 850 gram, PB: 31 cm, dan skor APGAR 5/6. Tidak ditemukan sel yang mengalami inflamasi pada vili chorionic. Bayi tetap hidup setelah dirawat di NICU selama 30 hari.
Kesimpulan: Interaksi maternal fetal yang optimal menjamin viabilitas fetus.

Kata kunci: Inflamasi, IUGR, Preeklamsia, Viabilitas Fetus, Preeklamsia.




Keywords


Fetus Viability, Inflammation, IUGR, Preeclampsia.

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References


Abalos E, Cuesta C, Grosso AL, Chou D, Say L. European Journal of Obstetrics & Gynecology and Reproductive Biology Global and regional estimates of preeclampsia and eclampsia : a systematic review. Eur J Obstet Gynecol [Internet]. 2013;170(1):1–7. Available from: http://dx.doi.org/10.1016/j.ejogrb.2013.05.005

Yang Y, Ray I Le, Zhu J, Zhang J, Hua J, Reilly M. Preeclampsia Prevalence , Risk Factors , and Pregnancy Outcomes in Sweden and China. JAMA Netw Open. 2021;4(5):1–14.

Mou AD, Barman Z, Hasan M, Miah R, Hafsa JM, Trisha A Das, et al. Prevalence of preeclampsia and the associated risk factors among pregnant women in Bangladesh. Sci Rep [Internet]. 2021;11(21339):1–9. Available from: https://doi.org/10.1038/s41598-021-00839-w

POGI. Pedoman Nasional Pelayanan Kedokteran Diagnosis dan Tata Laksana Pre-eklamsia. Jakarta: POGI; 2016. p. 1–14.

Magee LA, Brown MA, Hall DR, Gupte S, Hennessy A, Karumanchi SA, et al. Pregnancy Hypertension : An International Journal of Women ’ s Cardiovascular Health The 2021 International Society for the Study of Hypertension in Pregnancy classification , diagnosis & management recommendations for international practice ☆. Pregnancy Hypertens An Int J Women’s Cardiovasc Heal [Internet]. 2022;27(September 2021):148–69. Available from: https://doi.org/10.1016/j.preghy.2021.09.008

ACOG. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. Obstet Gynecol. 2020;135(6):e237–60.

Amaral LM, Wallace K, Owens M, Lamarca B. Pathophysiology and Current Clinical Management of Preeclampsia. Curr Hypertens Rep. 2017;1:19–21.

Tolunay HE, Eroglu H, Varli EN, Aksar M, Sahin D, Yucel A. Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation İntrauterin büyüme geriliği ile komplike olan gebeliklerde ilk. Turk J Obs Gynecol. 2020;17:98–101.

Fisher JJ, Bartho LA, Perkins A V, Holland OJ. Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy. Clin Exp Pharmacol Physiol. 2020 Jan;47(1):176–84.

Giussani DA, Phillips PS, Anstee S, Barker DJ. Effects of altitude versus economic status on birth weight and body shape at birth. Pediatr Res. 2001 Apr;49(4):490–4.

Burton GJ, Redman CW, Roberts JM, Moffett A. Pre-eclampsia : pathophysiology and clinical implications. BMJ. 2019;366:1–15.

Phipps E, Prasanna D, Brima W, Jim B. Preeclampsia: updates in pathogenesis, definitions, and guidelines. Clin J Am Soc Nephrol [Internet]. 2016;11(6):1102–13. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891761/

Gardosi J, Kady SM, Mcgeown P, Francis A, Tonks A. Classification of stillbirth by relevant condition at death ( ReCoDe ): population based cohort study. BMJ. 2005;(October):1113–7.

Malhotra A, Allison BJ, Castillo-Melendez M, Jenkin G, Polglase GR, Miller SL. Neonatal Morbidities of Fetal Growth Restriction: Pathophysiology and Impact. Front Endocrinol (Lausanne) [Internet]. 2019;10. Available from: https://www.frontiersin.org/article/10.3389/fendo.2019.00055

Bulmer JN, Williams PJ, Lash GE. Immune cells in the placental bed. Int J Dev Biol. 2010;294(October 2009):281–94.

Glover LE, Crosby D, Thiruchelvam U, Chorcora CN, Wingfield MB, Farrelly CO. Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis- ­associated infertility. Am J Reprod Immunol. 2018;79:1–9.

Faas MM, Vos P De. Uterine NK cells and macrophages in pregnancy. Placenta [Internet]. 2017;56:44–52. Available from: http://dx.doi.org/10.1016/j.placenta.2017.03.001

Yang F, Zheng Q, Jin L. Dynamic Function and Composition Changes of Immune Cells During Normal and Pathological Pregnancy at the Maternal-Fetal Interface. Front Immunol [Internet]. 2019;10. Available from: https://www.frontiersin.org/article/10.3389/fimmu.2019.02317

Kim CJ, Romero R, Chaemsaithong P, Kim J-S. Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance. Am J Obs Gynecol. 2015;213(313):1–42.




DOI: http://dx.doi.org/10.24198/obgynia/v6n1.407

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