Gambaran Klinis dan Histopatologi Kasus-kasus Perdarahan Uterus Abnormal di Rumah Sakit Sumber Waras Jakarta

Andriana Kumala Dewi; Sony Sugiharto; Angela Felicia Sunjaya; Anthony Paulo Sunjaya

doi:10.24198/obgynia.v3i1.185

Gambaran Klinis dan Histopatologi Kasus-kasus Perdarahan Uterus Abnormal di Rumah Sakit Sumber Waras Jakarta

Andriana Kumala Dewi, Sony Sugiharto, Angela Felicia Sunjaya, Anthony Paulo Sunjaya

Abstract

Latar Belakang: Kasus perdarahan uterus abnormal (PUA) sering ditemui pada praktek sehari-hari. Prevalensi pada usia reproduktif adalah sekitar 10-30% dan merupakan sebab sekitar 25% dari semua tindakan bedah di bidang ginekologi. Penelitian ini bertujuan untuk menemukan gambaran klinis serta gambaran hasil histopatologi apa saja yang sering ditemukan pada pasien dengan diagnosis PUA.
Metode: Penelitian ini adalah deskriptif cross sectional dengan data rekam medis. Data berasal dari pasien yang didiagnosis menderita PUA dan dilakukan tatalaksana operatif selama periode Januari sampai Desember 2018 dari RS Sumber Waras.
Hasil: Diperoleh 87 pasien dengan PUA yang menjalani tindakan operatif dan dilakukan pemeriksaan histopatologi selama periode penelitian. Perdarahan menstruasi yang tidak teratur dan dengan volume banyak menjadi keluhan paling sering ditemukan (37,8% dan 34,5%). Sedangkan, berdasar hasil gambaran histopatologi yang didapat, ditemukan pada mayoritas pasien ditemukan gambaran patologi struktural (PALM) yaitu 86,2%.
Kesimpulan: Berdasarkan klasifikasi PALM COEIN, kelainan struktural ditemukan sebagai penyebab utama PUA berdasar gambaran histopatologis.

Clinical and Histopathologic Profile of Patients with Abnormal Uterine Bleeding in Sumber Waras Hospital Jakarta

Abstract
Background: Abnormal uterine bleeding is a frequent presenting symptom in everyday practice. It has a prevalence of 10-30% in the reproductive age group and contributes to about 25% of all gynecologic surgical interventions. This study aims to ascertain the etiologies of patients diagnosed with abnormal uterine bleeding based on their clinical and histopathologic profile.
Method: This is a descriptive cross-sectional study based on medical records. Data was obtained from patients diagnosed with AUB with an operative intervention between January and December 2018 in Sumber Waras Hospital.
Result: There were 87 patients diagnosed with AUB who had undergone operative intervention and histopathologic testing during the study period. Irregular menstrual bleeding and heavy menstrual bleeding is the most common presenting symptom (37.8% and 34.5% respectively). Based on the histopathology results, structural causes of AUB (PALM) was found in most patients (86.2%).
Conclusion: Based on the PALM COEIN classification, structural causes were found to be the main etiology of AUB based on histopathologic diagnosis.

Key words: Abnormal uterine bleeding, PALM COEIN, leiomyoma, adenomyosis

Keywords

Perdarahan uterus abnormal, PALM COEIN, leiomioma, adenomiosis,

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DOI: http://dx.doi.org/10.24198/obgynia.v3i1.185